授权专利:

1. KCTD12蛋白在细胞周期调控中新应用;何庆瑜,钟颖;ZL201510051575.0

2. 普罗帕酮在制备治疗食管癌药物中的应用; 李斌,郑炜彬,何庆瑜;ZL201711021028.3

3. 一种检测结直肠癌中蛋白质组的方法; 李斌,胡会芳,何庆瑜;ZL201711004909.4

4. 五氟利多在制备治疗食管癌药物中的应用; 李斌,郑灿灿,何庆瑜;ZL201711202961.0

5. 盐酸氮卓斯汀在制备抑制结肠癌肿瘤生长药物中的应用;李斌,胡会芳,何庆瑜;ZL201711246087.0

6. 莲心碱高氯酸盐在制备抗结直肠癌药物中的应用; 李斌,何庆瑜,李杨葭;ZL201810527429.4

7. 阿伏苯宗在制备抗肿瘤药物中的应用;何庆瑜,杨杰,李斌;ZL201811032122.3

8. 莪术醇与TRAIL在制备抗肿瘤联合用药中的应用;何庆瑜,张静,汪洋,周烨;ZL201810802651.0

9. 欧前胡素在制备抑制食管癌肿瘤的药物中的应用;李斌,黄智豪,何庆瑜,许雯雯;ZL201711232441.4

10. 铑配合物在制备抗菌药物中的应用;何庆瑜,阳小燕,刘春元,孟苗;ZL201810651576.2

11. 一种利用精氨酸标记细菌的SILAC培养基及其制备方法与应用 ;孙雪松,韩俊隆,易叔红;ZL201610391015.4

12. CA2在鼻咽癌中的检测、治疗的应用 ;王通,罗彦彰,张涛;ZL201610968723.X

13. 完整冷冻保存及解冻细胞内核糖体新生肽链复合物的方法 ;孙黎,张弓,王通,金静洁;ZL201410387213.4

文章发表:

1. Xu WW, Huang ZH, Liao L, Zhang QH, Li JQ, Zheng CC, He Y, Luo TT, Wang Y, Hu HF, Zuo Q, Chen WY, Yang QS, Zhao JF, Qin YR, Xu LY, Li EM, Liao HX, Li B, He QY. “ Direct Targeting of CREB1 with Imperatorin Inhibits TGFβ2-ERK Signaling to Suppress Esophageal Cancer Metastasis.” Adv Sci. 2020 Jul 1;7(16):2000925. doi: 10.1002/advs.202000925.IF = 15.84

2. Liao L, Yao ZT, Fang WK, He QY, Xu WW, Li B. “Epigenetics in Esophageal Cancer: From Mechanisms to Therapeutics.” Small Methods. 2020 Aug . doi: 10.1002/smtd.202000391.IF = 12.13

3. Hong P, Liu QW, Xie Y, Zhang QH, Liao L, He QY, Li B, Xu WW. “Echinatin suppresses esophageal cancer tumor growth and invasion through inducing AKT/mTOR-dependent autophagy and apoptosis.” Cell Death Dis. 2020 Jul 13;11(7):524. doi: 10.1038/s41419-020-2730-7. IF = 6.304

4. Huang XH, Yan X, Zhang QH, Hong P, Zhang WX, Liu YP, Xu WW, Li B, He QY. “Direct targeting of HSP90 with daurisoline destabilizes β-catenin to suppress lung cancer tumorigenesis.” Cancer Lett. 2020 Oct 1;489:66-78. doi: 10.1016/j.canlet.2020.05.024.IF = 7.36

5. Zheng YD, Pan Y, He K, Li N, Yang D, Du GF, Ge R, He QY, Sun X. “SPD_1495 Contributes to Capsular Polysaccharide Synthesis and Virulence in Streptococcus pneumoniae.” mSystems. 2020 Feb 25;5(1):e00025-20. doi: 10.1128/mSystems.00025-20.IF = 6.633

6. Lu S, Zhang J, Lian X, Sun L, Meng K, Chen Y, Sun Z, Yin X, Li Y, Zhao J, Wang T, Zhang G, He QY. A hidden human proteome encoded by 'non-coding' genes. Nucleic Acids Res. 2019 Jul 24. pii: gkz646. doi: 10.1093/nar/gkz646. IF= 11.501

7. Wang Y , Zhang J, Li B, He QY. “Advances of Proteomics in Novel PTM Discovery: Applications in Cancer Therapy.” Small Methods. 2019 May 10; doi: 10.1002/smtd.201900041.IF = 12.13

8. Gao L, Hu Y, Tian Y, Fan Z, Wang K, Li H, Zhou Q, Zeng G, Hu X, Yu L, Zhou S, Tong X, Huang H, Chen H, Liu Q, Liu W, Zhang G, Zeng M, Zhou G, He QY, Ji H, Chen L. “Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition.” Nat Commun. 2019 Apr 10;10(1):1665. doi: 10.1038/s41467-019-09295-7.IF =12.121

9. Yang J, Xu WW, Hong P, Ye F, Huang XH, Hu HF, Zhang QH, Yan X, Li B, He QY. Adefovir dipivoxil sensitizes colon cancer cells to vemurafenib by disrupting the KCTD12-CDK1 interaction. Cancer Lett. 2019 Mar 11;451:79-91. doi: 10.1016/j.canlet.2019.02.050.IF = 7.36

10. Li B, Hong P, Zheng CC, Dai W, Chen WY, Yang QS, Han L, Tsao SW, Chan KT, Lee NPY, Law S, Xu LY, Li EM, Chan KW, Qin YR, Guan XY, Lung ML, He QY, Xu WW, Cheung AL. Identification of miR-29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance. Theranostics. 2019 Feb 28;9(6):1599-1613. doi: 10.7150/thno.30372.IF = 8.579

11. Xu WW, Li B, Zhao JF, Yang JG, Li JQ, Tsao SW, He QY, Cheung ALM. “IGF2 induces CD133 expression in esophageal cancer cells to promote cancer stemness.” Cancer Lett. 2018 Jul 1;425:88-100. doi: 10.1016/j.canlet.2018.03.039.IF = 7.36

12. Yang J, Li BHe QY. Significance of prohibitin domain family in tumorigenesis and its implication in cancer diagnosis and treatment. Cell Death Dis. 2018 May 21;9(6):580. doi: 10.1038/s41419-018-0661-3.IF = 6.304

13. Liu WT, Wang Y; Zhang J, Ye F, Huang XH, Li B, He QY. “A novel strategy of integrated microarray analysis identifies CENPA, CDK1 and CDC20 as a cluster of diagnostic biomarkers in lung adenocarcinoma.” Cancer lett.425:43-53; 2018 Mar 31. doi:10.1016/j.canlet.2018.03.043.IF = 7.36

14. Zhong Y, Yang J, Xu WW, Wang Y, Zheng CC, Li B, He QY. “KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition.” Oncogene. 2017 Nov 2;36(44):6177-6189.. doi: 10.1038/onc.2017.287.IF = 7.971

15. Wang Y, Zhang J, Huang ZH, Huang XH, Zheng WB, Yin XF, Li YL, Li B, He QY.  “Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop.” Cell Death Dis. 2017 Jun 15;8(6):e2876. doi: 10.1038/cddis.2017.265.IF = 6.304

16. Li B, Xu WW, Han L, Chan KT, Tsao SW, Lee NP, Law S, Xu LY, Li EM, Chan KW, Qin YR, Guan XY, He QY, Cheung AL. “MicroRNA-377 suppresses initiation and progression of esophageal cancer by inhibiting CD133 and VEGF.” Oncogene. 2017 Jul 13;36(28):3986-4000. doi: 10.1038/onc.2017.29. IF = 7.971

17. Xu WW, Li B, Guan XY, Chung SK, Wang Y, Yip YL, Law SY, Chan KT, Lee NP, Chan KW, Xu LY, Li EM, Tsao SW, He QY, Cheung AL. “Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression.” Nat Commun. 2017 Feb 10;8:14399. doi: 10.1038/ncomms14399.IF = 12.121

18. Li B, Xu WW, Guan XY, Qin YR, Law S, Lee NP, Chan KT, Tam PY, Li YY, Chan KW, Yuen HF, Tsao SW, He QY, Cheung AL. Competitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance.  Clin Cancer Res. 2016 Mar 1;22(5):1243-55. doi: 10.1158/1078-0432.CCR-15-1196. E IF = 10.107

19. Lian X, Guo J, Gu W, Cui Y, Zhong J, Jin J, He QY, Wang T,Zhang G. Genome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human Cells. PLoS Genet. 2016 Feb 29;12(2):e1005901. doi: 10.1371/journal.pgen.1005901.IF = 5.174

20. Wang Y, Huang ZH, Li YJ, He GW, Yu RY, Yang J, Liu WT, Li B, He QY. Dynamic quantitative proteomics characterization of TNF-α-induced necroptosis. Apoptosis 2016 Dec;21(12):1438-1446. doi: 10.1007/s10495-016-1300-z. IF = 4.543